Biology:Pyrobaculum asR3 small RNA

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xxx sRNA
RF02793.svg
Predicted secondary structure and sequence conservation of Pyrobaculum asRNA3
Identifiers
RfamRF02793
Other data
Domain(s)Archaea
GO0003729
SO0000077,0000370
PDB structuresPDBe

asR3 is an archeal small RNA identified in seven Pyrobaculum species. The genus-specific nature can indicate this could be recent, stable adaptation.[1] asR3 binds to the 3′-end of the tpi gene (triose-phosphate-isomerse).[2] The tpi mRNA has a conserved structural element located close to the stop codon. Binding of the asR3 may be able to compete against the formation of the tpi element structure and this may modulate the function of this highly conserved element.[1]

References

  1. 1.0 1.1 "Diversity of Antisense and Other Non-Coding RNAs in Archaea Revealed by Comparative Small RNA Sequencing in Four Pyrobaculum Species". Frontiers in Microbiology 3: 231. 2012. doi:10.3389/fmicb.2012.00231. PMID 22783241. 
  2. "On the three-dimensional structure and catalytic mechanism of triose phosphate isomerase". Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences 293 (1063): 159–171. June 1981. doi:10.1098/rstb.1981.0069. PMID 6115415. 

See also

Other archaeal sRNAs:

  • Archaeal H/ACA sRNA
  • Methanosarcina sRNA162