Biology:RABEPK
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 Generic protein structure example |
Rab9 effector protein with Kelch motifs also known as p40 is a protein that in humans is encoded by the RABEPK gene.[1][2]
Membrane-associated p40, in together with RAB9A, facilitates the transport of the mannose 6-phosphate receptor (MPR) from endosomes to the trans-Golgi network.[1]
Interactions
RABEPK has been shown to interact with RAB9A[1] and FYVE finger-containing phosphoinositide kinase.[3]
References
- ↑ 1.0 1.1 1.2 "A novel Rab9 effector required for endosome-to-TGN transport". J Cell Biol 138 (2): 283–90. Aug 1997. doi:10.1083/jcb.138.2.283. PMID 9230071.
- ↑ "Entrez Gene: RABEPK Rab9 effector protein with kelch motifs". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10244.
- ↑ Ikonomov, Ognian C; Sbrissa Diego; Mlak Krzysztof; Deeb Robert; Fligger Jason; Soans Aleric; Finley Russell L; Shisheva Assia (Dec 2003). "Active PIKfyve associates with and promotes the membrane attachment of the late endosome-to-trans-Golgi network transport factor Rab9 effector p40". J. Biol. Chem. 278 (51): 50863–71. doi:10.1074/jbc.M307260200. ISSN 0021-9258. PMID 14530284.
Further reading
- "TIP47 is a key effector for Rab9 localization.". J. Cell Biol. 173 (6): 917–26. 2006. doi:10.1083/jcb.200510010. PMID 16769818.
- "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. 2005. doi:10.1038/nature04209. PMID 16189514. Bibcode: 2005Natur.437.1173R.
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. 2004. doi:10.1101/gr.2596504. PMID 15489334.
- "DNA sequence and analysis of human chromosome 9.". Nature 429 (6990): 369–74. 2004. doi:10.1038/nature02465. PMID 15164053. Bibcode: 2004Natur.429..369H.
- "Control of nutrient-sensitive transcription programs by the unconventional prefoldin URI.". Science 302 (5648): 1208–12. 2003. doi:10.1126/science.1088401. PMID 14615539. Bibcode: 2003Sci...302.1208G.
- "Active PIKfyve associates with and promotes the membrane attachment of the late endosome-to-trans-Golgi network transport factor Rab9 effector p40.". J. Biol. Chem. 278 (51): 50863–71. 2004. doi:10.1074/jbc.M307260200. PMID 14530284.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
External links
- RABEPK human gene location in the UCSC Genome Browser.
- RABEPK human gene details in the UCSC Genome Browser.
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