Biology:SERPINB4

Generic protein structure example

Serpin B4 is a protein that in humans is encoded by the SERPINB4 gene.

See also

• Serpin

Further reading

• "Identification of a novel human serpin gene; cloning sequencing and expression of leupin.". FEBS Letters 373 (1): 61–5. 1995. doi:10.1016/0014-5793(95)01015-7. PMID 7589435. 
• "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. 1997. doi:10.1101/gr.6.9.791. PMID 8889548. 
• "A murine ortholog of the human serpin SCCA2 maps to chromosome 1 and inhibits chymotrypsin-like serine proteinases". Genomics 54 (2): 297–306. 1999. doi:10.1006/geno.1998.5586. PMID 9828132. 
• "Structural analysis of human SCC antigen 2 promoter". Biochim. Biophys. Acta 1444 (1): 111–6. 1999. doi:10.1016/s0167-4781(98)00259-0. PMID 9931463. 
• "Co-expression of the squamous cell carcinoma antigens 1 and 2 in normal adult human tissues and squamous cell carcinomas". J. Histochem. Cytochem. 48 (1): 113–22. 2000. doi:10.1177/002215540004800112. PMID 10653592. 
• "Simple modifications of the serpin reactive site loop convert SCCA2 into a cysteine proteinase inhibitor: a critical role for the P3' proline in facilitating RSL cleavage". Biochemistry 39 (24): 7081–91. 2000. doi:10.1021/bi000050g. PMID 10852705. 
• "Circulating serpin tumor markers SCCA1 and SCCA2 are not actively secreted but reside in the cytosol of squamous carcinoma cells". Int. J. Cancer 89 (4): 368–77. 2000. doi:10.1002/1097-0215(20000720)89:4<368::AID-IJC9>3.0.CO;2-6. PMID 10956412. 
• "Molecular cloning of human squamous cell carcinoma antigen 1 gene and characterization of its promoter". Biochim. Biophys. Acta 1518 (1–2): 124–31. 2001. doi:10.1016/s0167-4781(01)00174-9. PMID 11267667. 
• "Aberrant expression of serpin squamous cell carcinoma antigen 2 in human tumor tissues and cell lines: evidence of protection from tumor necrosis factor-mediated apoptosis". Biol. Chem. 383 (7–8): 1231–6. 2003. doi:10.1515/BC.2002.136. PMID 12437110. 
• "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M. 
• "SCCA2-like serpins mediate genetic predisposition to skin tumors". Cancer Res. 63 (8): 1871–5. 2003. PMID 12702576. 
• "Overexpression of squamous cell carcinoma antigen variants in hepatocellular carcinoma". Br. J. Cancer 90 (4): 833–7. 2004. doi:10.1038/sj.bjc.6601543. PMID 14970861. 
• "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. 2004. doi:10.1101/gr.2596504. PMID 15489334. 
• "Uteroglobin suppresses SCCA gene expression associated with allergic asthma". J. Biol. Chem. 280 (11): 9761–4. 2005. doi:10.1074/jbc.C400581200. PMID 15677460. 
• "Towards a proteome-scale map of the human protein-protein interaction network". Nature 437 (7062): 1173–8. 2005. doi:10.1038/nature04209. PMID 16189514. Bibcode: 2005Natur.437.1173R. 
• "Tumor-associated serpin, squamous cell carcinoma antigen stimulates matrix metalloproteinase-9 production in cervical squamous cell carcinoma cell lines". Int. J. Oncol. 27 (5): 1345–53. 2005. doi:10.3892/ijo.27.5.1345. PMID 16211231. 
• "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Research 16 (1): 55–65. 2006. doi:10.1101/gr.4039406. PMID 16344560. 
• "Serpin squamous cell carcinoma antigen inhibits UV-induced apoptosis via suppression of c-JUN NH2-terminal kinase". J. Cell Biol. 172 (7): 983–90. 2006. doi:10.1083/jcb.200508064. PMID 16549498. 

External links

• The MEROPS online database for peptidases and their inhibitors: I04.009
• SERPINB4+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)