Biology:SERPINB6

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A representation of the 3D structure of the protein myoglobin showing turquoise α-helices.
Generic protein structure example

Serpin B6 is a protein that in humans is encoded by the SERPINB6 gene.[1][2][3]

See also

References

  1. ↑ "Cloning and molecular characterization of a human intracellular serine proteinase inhibitor". Proc Natl Acad Sci U S A 90 (20): 9417–21. Nov 1993. doi:10.1073/pnas.90.20.9417. PMID 8415716. 
  2. ↑ "A serpin gene cluster on human chromosome 6p25 contains PI6, PI9 and ELANH2 which have a common structure almost identical to the 18q21 ovalbumin serpin genes". Cytogenet Cell Genet 82 (3–4): 273–7. Feb 1999. doi:10.1159/000015118. PMID 9858835. 
  3. ↑ "Entrez Gene: SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5269. 

Further reading

  • "Production and characterization of recombinant human proteinase inhibitor 6 expressed in Pichia pastoris". Biochim. Biophys. Acta 1252 (1): 28–34. 1995. doi:10.1016/0167-4838(95)00108-7. PMID 7548163. 
  • Coughlin P; Nicholl J; Sun J et al. (1995). "Chromosomal mapping of the human proteinase inhibitor 6 (PI6) gene to 6p25 by fluorescence in situ hybridization". Genomics 26 (2): 431–3. doi:10.1016/0888-7543(95)80240-M. PMID 7601482. 
  • Morgenstern KA; Sprecher C; Holth L et al. (1994). "Complementary DNA cloning and kinetic characterization of a novel intracellular serine proteinase inhibitor: mechanism of action with trypsin and factor Xa as model proteinases". Biochemistry 33 (11): 3432–41. doi:10.1021/bi00177a037. PMID 8136380. 
  • Morgenstern KA; Henzel WJ; Baker JB et al. (1993). "Isolation and characterization of an intracellular serine proteinase inhibitor from a monkey kidney epithelial cell line". J. Biol. Chem. 268 (29): 21560–8. PMID 8408007. 
  • "Identification and purification of a novel serine proteinase inhibitor". J. Biol. Chem. 268 (13): 9541–7. 1993. PMID 8486644. 
  • "Identification and characterization of the cytoplasmic antiproteinase (CAP) in human platelets. Evidence for the interaction of CAP with endogenous platelet proteins". J. Biol. Chem. 271 (12): 7160–7. 1996. doi:10.1074/jbc.271.12.7160. PMID 8636153. 
  • "Human cytoplasmic antiproteinase neutralizes rapidly and efficiently chymotrypsin and trypsin-like proteases utilizing distinct reactive site residues". J. Biol. Chem. 271 (24): 14526–32. 1996. doi:10.1074/jbc.271.24.14526. PMID 8662739. 
  • Scott FL; Paddle-Ledinek JE; Cerruti L et al. (1999). "Proteinase inhibitor 6 (PI-6) expression in human skin: induction of PI-6 and a PI-6/proteinase complex during keratinocyte differentiation". Exp. Cell Res. 245 (2): 263–71. doi:10.1006/excr.1998.4241. PMID 9851866. 
  • Mikolajczyk SD; Millar LS; Marker KM et al. (1999). "Identification of a novel complex between human kallikrein 2 and protease inhibitor-6 in prostate cancer tissue". Cancer Res. 59 (16): 3927–30. PMID 10463585. 
  • Saedi MS; Zhu Z; Marker K et al. (2002). "Human kallikrein 2 (hK2), but not prostate-specific antigen (PSA), rapidly complexes with protease inhibitor 6 (PI-6) released from prostate carcinoma cells". Int. J. Cancer 94 (4): 558–63. doi:10.1002/ijc.1501. PMID 11745444. 
  • Wistow G; Bernstein SL; Wyatt MK et al. (2002). "Expressed sequence tag analysis of adult human lens for the NEIBank Project: over 2000 non-redundant transcripts, novel genes and splice variants". Mol. Vis. 8: 171–84. PMID 12107413. 
  • Strausberg RL; Feingold EA; Grouse LH et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Strik MC; Wolbink A; Wouters D et al. (2004). "Intracellular serpin SERPINB6 (PI6) is abundantly expressed by human mast cells and forms complexes with beta-tryptase monomers". Blood 103 (7): 2710–7. doi:10.1182/blood-2003-08-2981. PMID 14670919. 
  • Ota T; Suzuki Y; Nishikawa T et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. 
  • Gerhard DS; Wagner L; Feingold EA et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Charron Y; Madani R; Nef S et al. (2006). "Expression of serpinb6 serpins in germ and somatic cells of mouse gonads". Mol. Reprod. Dev. 73 (1): 9–19. doi:10.1002/mrd.20385. PMID 16175637. 
  • Rual JF; Venkatesan K; Hao T et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514. 

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