Biology:SHPRH
From HandWiki
Generic protein structure example |
E3 ubiquitin-protein ligase SHPRH is an enzyme that in humans is encoded by the SHPRH gene.[1][2]
Function
SHPRH is a ubiquitously expressed protein that contains motifs characteristics of several DNA repair proteins, transcription factors, and helicases.[supplied by OMIM][2]
References
- ↑ "Cloning and characterization of a novel gene, SHPRH, encoding a conserved putative protein with SNF2/helicase and PHD-finger domains from the 6q24 region". Genomics 82 (2): 153–61. August 2003. doi:10.1016/S0888-7543(03)00121-6. PMID 12837266. https://zenodo.org/record/1260099.
- ↑ 2.0 2.1 "Entrez Gene: SHPRH SNF2 histone linker PHD RING helicase". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=257218.
Further reading
- "Human SHPRH suppresses genomic instability through proliferating cell nuclear antigen polyubiquitination". The Journal of Cell Biology 175 (5): 703–8. December 2006. doi:10.1083/jcb.200606145. PMID 17130289.
- "Human SHPRH is a ubiquitin ligase for Mms2-Ubc13-dependent polyubiquitylation of proliferating cell nuclear antigen". Proceedings of the National Academy of Sciences of the United States of America 103 (48): 18107–12. November 2006. doi:10.1073/pnas.0608595103. PMID 17108083.
- "Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization". Current Biology 14 (16): 1436–50. August 2004. doi:10.1016/j.cub.2004.07.051. PMID 15324660. http://faculty.washington.edu/scottjdw/pdfs/jin_curr_biol_2004_p1436.pdf.
- "Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA sequence". Nature 377 (6547 Suppl): 3–174. September 1995. PMID 7566098. http://www.columbia.edu/itc/biology/pollack/w4065/client_edit/readings/nature377_3.pdf.