Biology:SLC5A3
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Sodium/myo-inositol cotransporter is a protein that in humans is encoded by the SLC5A3 gene.[1][2]
Expression of the myo-inositol transport protein is regulated by osmotic stress.[3]
See also
References
- ↑ "The human osmoregulatory Na+/myo-inositol cotransporter gene (SLC5A3): molecular cloning and localization to chromosome 21". Genomics 25 (2): 507–13. Jul 1995. doi:10.1016/0888-7543(95)80052-N. PMID 7789985.
- ↑ "Entrez Gene: SLC5A3 solute carrier family 5 (inositol transporters), member 3". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6526.
- ↑ "TonEBP stimulates multiple cellular pathways for adaptation to hypertonic stress: Organic osmolyte-dependent and -independent pathways". AJP: Renal Physiology 300 (3): F707–F715. 2011. doi:10.1152/ajprenal.00227.2010. PMID 21209002.
Further reading
- "Cloning of the cDNa for a Na+/myo-inositol cotransporter, a hypertonicity stress protein.". J. Biol. Chem. 267 (9): 6297–301. 1992. PMID 1372904.
- "The 21q22.1 STS marker, VN02 (EST00541 cDNA), is part of the 3' sequence of the human Na+/myo-inositol cotransporter (SLC5A3) gene.". Cytogenet. Cell Genet. 73 (1–2): 77–8. 1996. doi:10.1159/000134311. PMID 8646889.
- "The structural organization of the human Na+/myo-inositol cotransporter (SLC5A3) gene and characterization of the promoter". Genomics 46 (3): 459–65. 1998. doi:10.1006/geno.1997.5055. PMID 9441750.
- "Human Na(+)-myo-inositol cotransporter gene: alternate splicing generates diverse transcripts". Am. J. Physiol. 274 (5 Pt 1): C1215–25. 1998. PMID 9612208.
- "Transcription of the Sodium/myo-Inositol Cotransporter Gene Is Regulated by Multiple Tonicity-responsive Enhancers Spread over 50 Kilobase Pairs in the 5′-Flanking Region". J. Biol. Chem. 273 (32): 20615–21. 1998. doi:10.1074/jbc.273.32.20615. PMID 9685419.
- "The DNA sequence of human chromosome 21". Nature 405 (6784): 311–9. 2000. doi:10.1038/35012518. PMID 10830953.
- "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. 2004. doi:10.1038/ng1285. PMID 14702039.
- "Sequence Comparison of Human and Mouse Genes Reveals a Homologous Block Structure in the Promoter Regions". Genome Res. 14 (9): 1711–8. 2004. doi:10.1101/gr.2435604. PMID 15342556.
- "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. 2006. doi:10.1101/gr.4039406. PMID 16344560.
- "SLC5A8 triggers tumor cell apoptosis through pyruvate-dependent inhibition of histone deacetylases". Cancer Res. 66 (24): 11560–4. 2007. doi:10.1158/0008-5472.CAN-06-1950. PMID 17178845.
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