Biology:SNX26
From HandWiki
Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
TC10/CDC42 GTPase-activating protein is an enzyme that in humans is encoded by the SNX26 gene.[1][2][3]
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. The specific function of this protein has not been elucidated. Alternative splice variants have been described but their full length nature has not been determined.[3]
References
- ↑ "Human RhoGAP domain-containing proteins: structure, function and evolutionary relationships". FEBS Lett 528 (1–3): 27–34. Sep 2002. doi:10.1016/S0014-5793(02)03331-8. PMID 12297274.
- ↑ "Sorting out the cellular functions of sorting nexins". Nat Rev Mol Cell Biol 3 (12): 919–31. Dec 2002. doi:10.1038/nrm974. PMID 12461558.
- ↑ 3.0 3.1 "Entrez Gene: SNX26 sorting nexin 26". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=115703.
Further reading
- "The Phox homology (PX) domain, a new player in phosphoinositide signalling.". Biochem. J. 360 (Pt 3): 513–30. 2002. doi:10.1042/0264-6021:3600513. PMID 11736640.
- "Human chromosome 19 and related regions in mouse: conservative and lineage-specific evolution.". Science 293 (5527): 104–11. 2001. doi:10.1126/science.1060310. PMID 11441184.
- "A large family of endosome-localized proteins related to sorting nexin 1.". Biochem. J. 358 (Pt 1): 7–16. 2001. doi:10.1042/0264-6021:3580007. PMID 11485546.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
- "TCGAP, a multidomain Rho GTPase-activating protein involved in insulin-stimulated glucose transport.". EMBO J. 22 (11): 2679–91. 2003. doi:10.1093/emboj/cdg262. PMID 12773384.
- "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. 2004. doi:10.1038/ng1285. PMID 14702039.
- "The DNA sequence and biology of human chromosome 19.". Nature 428 (6982): 529–35. 2004. doi:10.1038/nature02399. PMID 15057824. Bibcode: 2004Natur.428..529G.
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. 2004. doi:10.1101/gr.2596504. PMID 15489334.
- "Physical and functional interaction of Fyn tyrosine kinase with a brain-enriched Rho GTPase-activating protein TCGAP.". J. Biol. Chem. 281 (33): 23611–9. 2006. doi:10.1074/jbc.M511205200. PMID 16777849.
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