Biology:Small nucleolar RNA SNORA11
From HandWiki
| Small nucleolar RNA SNORA11 | |
|---|---|
 Predicted secondary structure and sequence conservation of SNORA11 | |
| Identifiers | |
| Symbol | SNORA11 |
| Rfam | RF00614 |
| Other data | |
| RNA type | Gene; snRNA; snoRNA; H/ACA-box |
| Domain(s) | Eukaryota |
| GO | 0006396 0005730 |
| SO | 0000594 |
| PDB structures | PDBe |
In molecular biology, small nucleolar RNA SNORA11 (also known as U107) is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA).
U107 has a predicted hairpin-hinge-hairpin-tail structure and is predicted to be a member of the H/ACA box class of snoRNAs that guide the sites of modification of uridines to pseudouridines.[1] This snoRNA was identified by RT-PCR from blood cells and its expression confirmed by Northern blot analysis.[2] There is no predicted RNA target for this guide snRNA.[3]
References
- ↑ "Human box H/ACA pseudouridylation guide RNA machinery". Molecular and Cellular Biology 24 (13): 5797–5807. July 2004. doi:10.1128/MCB.24.13.5797-5807.2004. PMID 15199136.
- ↑ "A novel experimental approach for systematic identification of box H/ACA snoRNAs from eukaryotes". Nucleic Acids Research 33 (22): e194. December 2005. doi:10.1093/nar/gni185. PMID 16361266.
- ↑ "snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAs". Nucleic Acids Research 34 (Database issue): D158–162. January 2006. doi:10.1093/nar/gkj002. PMID 16381836.
External links
- Page for Small nucleolar RNA SNORA11 at Rfam
- Entry for SNORA11 at snoRNABase
- HGNC page for Small nucleolar RNA SNORA11
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