Biology:Sulmazole
From HandWiki
Short description: Chemical compound
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| Formula | C14H13N3O2S |
| Molar mass | 287.34 g·mol−1 |
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Sulmazole is a cardiotonic drug.[1] Sulmazole has the chemical formula C14H13N3O2S[2] and a molecular weight of 287.34 g/mol.[2]
Sulmazole has been shown to improve cardiac index and reduce pulmonary capillary wedge pressure without significant changes in a person's heart rate or arterial pressure.[3] Sulmazole inhibits the A1 adenosine receptor and functionally blocks Gi, an inhibitory regulator.[1] Sulmazole is also a phosphodiesterase inhibitor.[3] Sulmazole is classified as an imidazopyridine and a sulfoxide.[2] Sulmazole can be taken intravenously or orally.[3] Side effects from sulmazole include blurring vision and temporary color blindness.[3]
References
- ↑ 1.0 1.1 "The new cardiotonic agent sulmazole is an A1 adenosine receptor antagonist and functionally blocks the inhibitory regulator, Gi". Molecular Pharmacology 33 (4): 441–8. April 1988. PMID 3128727.
- ↑ 2.0 2.1 2.2 PubChem. "Sulmazole" (in en). https://pubchem.ncbi.nlm.nih.gov/compound/5353.
- ↑ 3.0 3.1 3.2 3.3 "NCATS Inxight: Drugs — SULMAZOLE" (in en). https://drugs.ncats.io/substance/HK56EH9K44.
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