Biology:WDR45L
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 Generic protein structure example |
WD repeat domain phosphoinositide-interacting protein 3 (WIPI-3), also known as WD repeat-containing protein 45-like is a protein that in humans is encoded by the gene.[1]
Structure and function
WIPI-3 is a member of the WIPI or SVP1 family of WD40 repeat-containing proteins. The protein contains seven WD40 repeats that are thought to fold into a beta-propeller structure that mediates protein–protein interactions, and a conserved motif for interaction with phospholipids.[1]
See also
References
Further reading
- "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.". Nat. Biotechnol. 22 (6): 707–16. 2004. doi:10.1038/nbt971. PMID 15146197.
- "PtdIns-specific MPR pathway association of a novel WD40 repeat protein, WIPI49.". Mol. Biol. Cell 15 (6): 2652–63. 2004. doi:10.1091/mbc.E03-10-0732. PMID 15020712.
- "WIPI-1alpha (WIPI49), a member of the novel 7-bladed WIPI protein family, is aberrantly expressed in human cancer and is linked to starvation-induced autophagy.". Oncogene 23 (58): 9314–25. 2004. doi:10.1038/sj.onc.1208331. PMID 15602573.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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