Biology:Yfr1
From HandWiki
Short description: Cyanobacterial functional RNA
| Cyanobacterial functional RNA 1 | |
|---|---|
 Predicted secondary structure and sequence conservation of Yfr1 | |
| Identifiers | |
| Symbol | Yfr1 |
| Rfam | RF01116 |
| Other data | |
| RNA type | Gene; sRNA |
| Domain(s) | Bacteria |
| SO | 0001263 |
| PDB structures | PDBe |
Yfr1 is a Cyanobacterial functional RNA that was identified by a comparative genome based screen for RNAs in cyanobacteria.[1] Further analysis has shown that the RNA is well conserved and highly expressed in cyanobacteria.[2] and is required for growth under several stress condition[3] Bioinformatics research combined with follow-up experiments have shown that Yfr1 inhibits the translation of the proteins PMM1119 and PMM1121 by an antisense interaction by base pairing at the ribosomal binding site.[4]
See also
- Yfr2 RNA
- Cyano-S1 RNA motif
- Cyano-2 RNA motif
References
- ↑ "Identification of cyanobacterial non-coding RNAs by comparative genome analysis.". Genome Biol 6 (9): R73. 2005. doi:10.1186/gb-2005-6-9-r73. PMID 16168080.
- ↑ "A motif-based search in bacterial genomes identifies the ortholog of the small RNA Yfr1 in all lineages of cyanobacteria.". BMC Genomics 8: 375. 2007. doi:10.1186/1471-2164-8-375. PMID 17941988.
- ↑ "A cyanobacterial non-coding RNA, Yfr1, is required for growth under multiple stress conditions". Plant Cell Physiol 48 (9): 1309–1318. 2007. doi:10.1093/pcp/pcm098. PMID 17664182.
- ↑ "Seed-based INTARNA prediction combined with GFP-reporter system identifies mRNA targets of the small RNA Yfr1". Bioinformatics 26 (1): 1–5. 2010. doi:10.1093/bioinformatics/btp609. PMID 19850757.
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