Chemistry:1,2-Bis(dichlorophosphino)benzene
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| Names | |
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| Preferred IUPAC name
(1,2-Phenylene)bis(phosphonous dichloride) | |
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| Properties | |
| C6H4Cl4P2 | |
| Molar mass | 279.85 g·mol−1 |
| Appearance | colorless liquid |
| Boiling point | 97–99 °C (207–210 °F; 370–372 K) 0.001 torr |
| Hazards | |
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| GHS Signal word | Danger |
| H314 | |
| P260, P264, P280, P301+330+331, P303+361+353, P304+340, P305+351+338, P310, P321, P363, P405, P501 | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
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1,2-Bis(dichlorophosphino)benzene is an organophosphorus compound with the formula C6H4(PCl2)2. A viscous colorless liquid, it is a precursor to chelating diphosphines of the type C6H4(PR2)2.[1] It is prepared from 1,2-dibromobenzene by sequential lithiation followed by treatment with (Et2N)2PCl (Et = ethyl), which affords C6H4[P(NEt2)2]2. This species is finally cleaved with hydrogen chloride:[2]
- C6H4[P(NEt2)2]2 + 8 HCl → C6H4(PCl2)2 + 4 Et2NH2Cl
Related compounds
References
- ↑ Hatakeyama, Takuji; Hashimoto, Toru; Kondo, Yoshiyuki; Fujiwara, Yuichi; Seike, Hirofumi; Takaya, Hikaru; Tamada, Yoshinori; Ono, Teruo et al. (2010). "Iron-Catalyzed Suzuki−Miyaura Coupling of Alkyl Halides". Journal of the American Chemical Society 132 (31): 10674–10676. doi:10.1021/ja103973a. PMID 20681696.
- ↑ Reetz, Manfred T.; Moulin, Dominique; Gosberg, Andreas (2001). "BINOL-Based Diphosphonites as Ligands in the Asymmetric Rh-Catalyzed Conjugate Addition of Arylboronic Acids". Organic Letters 3 (25): 4083–4085. doi:10.1021/ol010219y. PMID 11735590.
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