Chemistry:2,3,4,5-Tetramethoxyamphetamine

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Short description: Chemical compound
2,3,4,5-Tetramethoxyamphetamine
2,3,4,5-Tetramethoxyamphetamine.svg
Legal status
Legal status
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
Chemical and physical data
FormulaC13H19NO4
Molar mass253.298 g·mol−1
3D model (JSmol)
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Tetramethoxyamphetamine, or 2,3,4,5-tetramethoxyamphetamine, is a lesser-known psychedelic drug and a substituted amphetamine. Tetramethoxyamphetamine was first synthesized by Alexander Shulgin. In his book PiHKAL (Phenethylamines i Have Known And Loved), the minimum dosage is listed as 50 mg, and the duration unknown. Tetramethoxyamphetamine produces a threshold, mydriasis, and a headache. Limited data exists about its pharmacological properties, metabolism, and toxicity.[1][2][3]

References

  1. "Structure-activity studies on hallucinogenic amphetamines using molecular connectivity". Journal of Medicinal Chemistry 20 (12): 1631–6. December 1977. doi:10.1021/jm00222a019. PMID 592329. 
  2. "Structure-activity correlations for psychotomimetics. 1. Phenylalkylamines: electronic, volume, and hydrophobicity parameters". Journal of Medicinal Chemistry 33 (2): 687–702. February 1990. doi:10.1021/jm00164a036. PMID 2299636. 
  3. "The frontier orbital phase angles: novel QSAR descriptors for benzene derivatives, applied to phenylalkylamine hallucinogens". Journal of Medicinal Chemistry 41 (20): 3845–56. September 1998. doi:10.1021/jm980144c. PMID 9748359. 

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