Chemistry:2-Fluorobenzoic acid
From HandWiki
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| Names | |
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| Preferred IUPAC name
2-Fluorobenzoic acid | |
| Other names
o-Fluorobenzoic acid
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| Identifiers | |
3D model (JSmol)
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PubChem CID
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| Properties | |
| C7H5FO2 | |
| Molar mass | 140.113 g·mol−1 |
| Melting point | 126 °C (259 °F; 399 K) |
| log P | 1.856 |
| Acidity (pKa) | 3.27 |
| Hazards | |
| Safety data sheet | Laboratory Chemical Safety Summary |
| Flash point | 102 °C (216 °F; 375 K) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| Infobox references | |
Tracking categories (test):
2-Fluorobenzoic acid is an aromatic organic compound with the formula FC6H4CO2H. It is one of three isomeric fluorobenzoic acids. Its conjugate base is 2-fluorobenzoate. The compound is an irritant.
Its metabolism has been studied extensively in the field of microbiology.[1][2] Its conjugate base is part of the pathway of 2-fluorobiphenyl metabolism by Pseudomonas pseudoalcaligenes.
See also
- 4-Fluorobenzoic acid, the para isomer
- 3-Fluorobenzoic acid, the meta isomer
- 2-Chlorobenzoic acid
References
- ↑ Milne, G. W. A.; P. Goldman; J. L. Holtzman (1968). "The metabolism of 2-fluorobenzoic acid. Studies with 18O2". J. Biol. Chem. 243 (20): 5374–5376. doi:10.1016/S0021-9258(18)91959-9. PMID 5702050. http://www.jbc.org/content/243/20/5374.
- ↑ Murphy, Cormac D.; Quirke, Shane; Balogun, Olufunmilayo (2008). "Degradation of fluorobiphenyl by Pseudomonas pseudoalcaligenesKF707". FEMS Microbiology Letters 286 (1): 45–9. doi:10.1111/j.1574-6968.2008.01243.x. PMID 18616594.
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