Chemistry:2-Hydroxy-3-morpholinopropanesulfonic acid
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Names | |
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Preferred IUPAC name | |
Other names
MOPSO, 3-morpholino-2-hydroxypropanesulfonic acid, 3-morpholino-2HOPSA
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Identifiers | |
3D model (JSmol)
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EC Number |
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PubChem CID
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UNII | |
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Properties | |
C7H15NO5S | |
Molar mass | 225.259 g/mol |
Appearance | White crystalline powder |
Melting point | 270–290 °C (518–554 °F; 543–563 K) |
Acidity (pKa) | 6.9[3] |
Hazards | |
Main hazards | Irritant |
GHS Signal word | Warning |
H315, H319, H335 | |
P261, P264, P271, P280, P302+352, P304+340, P305+351+338, P312, P321, P332+313, P337+313, P362, P403+233, P405, P501 | |
Flash point | Non-flammable |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
Infobox references | |
MOPSO is a zwitterionic organic chemical buffering agent; one of Good's buffers. MOPSO and MOPS (3-morpholinopropanesulfonic acid) are chemically similar, differing only in the presence of a hydroxyl group on the C-2 of the propane moiety. It has a useful pH range of 6.5-7.9 in the physiological range, making it useful for cell culture work. It has a pKa of 6.9 with ΔpKa/°C of -0.015 and a solubility in water at 0°C of 0.75 M.
MOPSO has been used as a buffer component for:[4]
- Copper analysis via:
- Flow injection micellar technique of the catalytic reaction of 3-methyl-2-benzothiazolinone hydrazone and N-ethyl-N-(2-hydroxy-3-sulfopropyl)-3,5-dimethoxyaniline
- Electrospray ionization quadrupole time-of-flight mass spectroscopy to measure MOPSO-copper chelated complexes
- Discontinuous gel electrophoresis on rehydratable polyacrylamide gels
- Buffered charcoal yeast extract agar
- Fixing cells in urine in a buffered alcohol
- Testing crude oil bioremediation products in marine environments
See also
References
- ↑ "Compound Summary for CID 109333". 2005-03-27. https://pubchem.ncbi.nlm.nih.gov/compound/Mopso#section=Top.
- ↑ "MOPSO". http://www.sigmaaldrich.com/catalog/product/sigma/m8389?lang=en®ion=US.
- ↑ "Biological Buffers". http://www.sigmaaldrich.com/life-science/metabolomics/bioultra-reagents/biological-buffers.html.
- ↑ "MOPSO sodium salt". https://www.sigmaaldrich.com/content/dam/sigma-aldrich/docs/Sigma/Product_Information_Sheet/1/m8767pis.pdf.
![]() | Original source: https://en.wikipedia.org/wiki/2-Hydroxy-3-morpholinopropanesulfonic acid.
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