Chemistry:3,3-Diphenylpropylamine

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3,3-Diphenylpropylamine is a form of diphenylpropylamine.

It is commonly conjugated to another agent giving a "bifunctional" molecule. Some such agents are used to treat cardiovascular diseases.

3,3-Diphenylpropylamine derivatives
Name Identifier Chemical structure
BIIA 0388 CID:9958467 [337359-07-6] 100px
BZP derivative [1] 100px
Droprenilamine [57653-27-7] 100px
Delucemine [186495-49-8 ] 100px
Fendiline [13042-18-7] 100px
Lercanidipine [100427-26-7] 100px
KD-983 [50597-65-4] 100px
Mepramidil [23891-60-3] 100px
Milverine [75437-14-8] 100px
PF 244 Fb: [52017-07-9] 100px
Prenylamine [390-64-7] 100px
SoRI-20041 now SRI-20041 100px
Tiopropamine [39516-21-7] 100px
CB1 receptor ligand [117-34-0] [5586-73-2][2] 100px
5-APDI [3] 100px
SRI-29213 PC121377378[4] 100px


References

  1. Tadayuki Suzuki & Toshiharu Megumi, U.S. Patent 3,957,790 (1976 to Tokyo Tanabe Co Ltd).
  2. "Novel sterically hindered cannabinoid CB1 receptor ligands". Bioorganic & Medicinal Chemistry 16 (15): 7510–7515. August 2008. doi:10.1016/j.bmc.2008.06.001. PMID 18579386. 
  3. Frank Troxler & Albert Hofman, OA01894 (1970 to Sandoz KK).
  4. Rothman RB, Ananthan S, Partilla JS, Saini SK, Moukha-Chafiq O, Pathak V, Baumann MH. Studies of the biogenic amine transporters 15. Identification of novel allosteric dopamine transporter ligands with nanomolar potency. J Pharmacol Exp Ther. 2015 Jun;353(3):529-38. doi: 10.1124/jpet.114.222299. Epub 2015 Mar 18. PMID: 25788711; PMCID: PMC4429677.