Chemistry:6-Ketoprogesterone

6-Ketoprogesterone

Names
IUPAC name Pregn-4-ene-3,6,20-trione
Other names 6-Ketoprogesterone;6-Oxoprogesterone
Identifiers
CAS Number	2243-08-5
3D model (JSmol)	Interactive image
ChemSpider	222301
MeSH	C111515
PubChem CID	104796
UNII	2698PNJ55U Y
InChI InChI=1S/C21H28O3/c1-12(22)15-4-5-16-14-11-19(24)18-10-13(23)6-8-21(18,3)17(14)7-9-20(15,16)2/h10,14-17H,4-9,11H2,1-3H3/t14-,15+,16-,17-,20+,21+/m0/s1 Key: LASCNIPXMJNRGS-HGUQNLGYSA-N InChI=1/C21H28O3/c1-12(22)15-4-5-16-14-11-19(24)18-10-13(23)6-8-21(18,3)17(14)7-9-20(15,16)2/h10,14-17H,4-9,11H2,1-3H3/t14-,15+,16-,17-,20+,21+/m0/s1 Key: LASCNIPXMJNRGS-HGUQNLGYBS
SMILES O=C4\C=C3\C(=O)C[C@@H]1[C@H](CC[C@@]2([C@@H](C(=O)C)CC[C@@H]12)C)[C@@]3(C)CC4
Properties
Chemical formula	C21H28O3
Molar mass	328.452 g·mol−1
Density	1.14 g/cm3
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Tracking categories (test):

• SizeSet

6-Ketoprogesterone is an orally active oxidized form of progesterone that contains a keto group at position-6.

Further reading

Paul B. Glickman, MD; Robert H. Palmer, MD; Attallah Kappas, MD (July 1964). "Steroid Fever And Inflammation". Arch Intern Med 114 (1): 46–58. doi:10.1001/archinte.1964.03860070092009. PMID 14152129.