Chemistry:AP503
From HandWiki
AP503 is a chemical compound which acts as an agonist at the androgen receptor GPR133. It increases muscle growth and bone density in animal models, and may have potential applications in the treatment of osteoporosis and sarcopenia in the elderly.[1][2]
See also
- GL64
References
- ↑ "Identification, structure, and agonist design of an androgen membrane receptor". Cell 188 (6): 1589–1604.e24. March 2025. doi:10.1016/j.cell.2025.01.006. PMID 39884271.
- ↑ "The mechanosensitive adhesion G protein-coupled receptor 133 (GPR133/ADGRD1) enhances bone formation". Signal Transduction and Targeted Therapy 10 (1). June 2025. doi:10.1038/s41392-025-02291-y. PMID 40583059.
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