Chemistry:Actisomide
From HandWiki
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| Names | |
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| Preferred IUPAC name
(4R,4aR)-4-{2-[Di(propan-2-yl)amino]ethyl}-1-methyl-4-phenyl-4,4a,5,6,7,8-hexahydro-3H-pyrido[1,2-c]pyrimidin-3-one | |
| Identifiers | |
3D model (JSmol)
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| ChEMBL | |
| ChemSpider | |
| KEGG | |
| MeSH | C051827 |
PubChem CID
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| Properties | |
| C23H35N3O | |
| Molar mass | 369.553 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| Infobox references | |
Tracking categories (test):
Actisomide is an antiarrhythmic drug[1] that is made from disopyramide.
Synthesis
Actisomide synthesis:[2]
References
- ↑ Cook, CS; Rozek, LF; Stolzenbach, J; Anderson, S; Schoenhard, GL; Karim, A (1993). "Pharmacokinetics of a novel antiarrhythmic drug, actisomide". Pharmaceutical Research 10 (3): 427–33. doi:10.1023/a:1018900725050. PMID 8464818.
- ↑ Chorvat, Robert J.; Prodan, Kathleen A.; Adelstein, Gilbert W.; Rydzewski, Robert M.; McLaughlin, Kathleen T.; Stamm, Margarete H.; Frederick, Leo G.; Schniepp, Henry C. et al. (1985). "Synthesis and structure-activity relationships of a new series of antiarrhythmic agents: 4,4-disubstituted hexahydro-3H-pyrido[1,2-c]pyrimidin-3-ones and related compounds". Journal of Medicinal Chemistry 28 (9): 1285–91. doi:10.1021/jm00147a029. PMID 4032431.
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