Chemistry:Auranthine
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| IUPAC name
6,7,7a,8-Tetrahydroquinazolino[3’,2’:1,6]pyrido[2,3-b] [1,4]benzodiazepine-9,16-dione
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3D model (JSmol)
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PubChem CID
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| Properties | |
| C19H14N4O2 | |
| Molar mass | 330.347 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
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Tracking categories (test):
Auranthine is an antimicrobial chemical compound isolated from a nephrotoxic strain[1] of Penicillium fungus, Penicillium aurantiogriseum.[2]
A total synthesis of auranthine has been reported.[3]
References
- ↑ MacGeorge, K. M; Mantle, P. G (1990). "Nephrotoxicity of Penicillium aurantiogriseum and P. Commune from an endemic nephropathy area of Yugoslavia". Mycopathologia 112 (3): 139–45. doi:10.1007/bf00436643. PMID 2089255.
- ↑ Yeulet, Stephanie E; Mantle, Peter G; Bilton, John N; Rzepa, Henry S; Sheppard, Richard N (1986). "Auranthine, a new benzodiazepinone metabolite of Penicillium aurantiogriseum". Journal of the Chemical Society, Perkin Transactions 1: 1891. doi:10.1039/P19860001891.
- ↑ Kshirsagar, Umesh A; Puranik, Vedavati G; Argade, Narshinha P (2010). "Total Synthesis of Proposed Auranthine". The Journal of Organic Chemistry 75 (8): 2702–2705. doi:10.1021/jo100400z. PMID 20302381.
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