Chemistry:Cannabisol
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| Formula | C43H60O4 |
| Molar mass | 640.949 g·mol−1 |
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Cannabisol was a cannabis-derived medication in the early 20th century in Sweden. The drug was used to treat depression until the 1950s.[1] The 1934 Year Book of the American Pharmaceutical Association states, "A 1.2 p.c. solution of standardized cannabinol, the active constituent of Cannabis indica, is given in doses of 8 to 20 drops three times a day for depression."[2] The Natural Library of Medicine states, "Cannabisol (1), a unique dimer of Δ9-tetrahydrocannabinol (Δ9-THC) with a methylene bridge, was isolated from Cannabis sativa.[3] This is the first example of a C-bridged dimeric cannabinoid. The structure of 1 was unambiguously deduced by HRESIMS, GCMS, and NMR spectroscopy. A plausible biogenesis of 1 is described."[4][5]
References
- ↑ Decorte, Tom (11 February 2016). World Wide Weed: Global Trends in Cannabis Cultivation and its Control. Routledge. pp. 53–. ISBN 978-1-134-78521-6. https://books.google.com/books?id=Dv6NCwAAQBAJ&pg=PT53.
- ↑ Year Book of the American Pharmaceutical Association. Washington, D.C.: American Pharmaceutical Association. 1934. p. 86. https://books.google.com/books?id=2U5LAAAAMAAJ.
- ↑ "Life, Before and After CBD Became Prominent". Safer Products. https://safercbd.com/cannabisol-the-truth-behind-cbd-and-its-origins/.
- ↑ "Cannabis sativa". Tetrahedron Letters 53 (28): 3560–3562. July 2012. doi:10.1016/j.tetlet.2012.04.139. PMID 27695140.
- ↑ "CBD Oil Benefits". https://holisticwatch.com/what-are-the-benefits-of-cbd/. Sunday, March 8, 2020
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