Chemistry:Cinfenine
From HandWiki
Cinfenine (INN) is a drug described as an antidepressant and coronary vasodilator which was never marketed.[1][2][3] It was first described in the literature by 1970.[1][4] The drug is similar in chemical structure to the modafinil derivative and atypical dopamine reuptake inhibitor JJC8-016, as well as to the antihistamine and anticholinergic diphenhydramine and derivatives of diphenhydramine like ebastine.[1][5] Other notable analogues acting as dopamine reuptake inhibitors have been synthesized as well.[6]
See also
References
- ↑ 1.0 1.1 1.2 The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer US. 2014. p. 278. ISBN 978-1-4757-2085-3. https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA278. Retrieved 20 October 2024.
- ↑ Use of stems in the selection of International Nonproprietary Names (INN) for pharmaceutical substances. World Health Organization. 2024. p. 102. ISBN 978-92-4-009938-8. https://iris.who.int/bitstream/handle/10665/379226/9789240099388-eng.pdf.
- ↑ "CINFENINE". Inxight Drugs. National Center for Advancing Translational Sciences (NCATS). https://drugs.ncats.io/substance/P26FL0O04P.
- ↑ "Diphenylmethoxyaethylaminoderivate und Verfahren zu ihrer Herstellung" DE patent 1936206, published 22 January 1970
- ↑ "Cinfenine". PubChem. U.S. National Library of Medicine. https://pubchem.ncbi.nlm.nih.gov/compound/6443800.
- ↑ "Synthesis and dopamine transporter affinity of chiral 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(2-hydroxypropyl)piperazines as potential cocaine abuse therapeutic agents". Bioorg Med Chem Lett 13 (3): 553–556. February 2003. doi:10.1016/s0960-894x(02)00940-x. PMID 12565970.
 |  |
