Chemistry:Crelosidenib
From HandWiki
Crelosidenib is an investigational new drug that is being evaluated for the treatment of cancer. It acts as a selective inhibitor of isocitrate dehydrogenase 1 (IDH1), an enzyme that plays a crucial role in cellular metabolism and is frequently mutated in various cancers, including cholangiocarcinoma.[1][2]
References
- ↑ "Clinical development of IDH1 inhibitors for cancer therapy". Cancer Treatment Reviews 103. February 2022. doi:10.1016/j.ctrv.2021.102334. PMID 34974243.
- ↑ "Emerging targeted therapies and strategies to overcome resistance in biliary tract cancers". Critical Reviews in Oncology/Hematology 199. July 2024. doi:10.1016/j.critrevonc.2024.104388. PMID 38754771.
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