Chemistry:D75-4590
From HandWiki
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| Names | |
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| IUPAC name
1-{[2-(Diethylamino)ethyl]amino}-2-ethyl-3-methylpyrido[1,2-a]benzimidazole-4-carbonitrile
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| Other names
4-[2-(Diethylamino)ethylamino]-3-ethyl-2-methyl-4a,9-diaza-3,4-dihydrofluorene-1-carbonitrile
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| Identifiers | |
3D model (JSmol)
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PubChem CID
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| Properties | |
| C21H27N5 | |
| Molar mass | 349.473 g/mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| Infobox references | |
Tracking categories (test):
D75-4590 is an antifungal pyridobenzimidazole derivative that inhibits β-glucan synthesis. D11-2040 and D21-6076 are antifungal derivatives of D75-4590.[1][2]
References
- ↑ Kitamura, Akihiro; Someya, Kazuhiko; Hata, Masato; Nakajima, Ryohei; Takemura, Makoto (2008). "Discovery of a Small-Molecule Inhibitor of β-1,6-Glucan Synthesis". Antimicrobial Agents and Chemotherapy 53 (2): 670–7. doi:10.1128/AAC.00844-08. PMID 19015325.
- ↑ Kitamura, Akihiro; Someya, Kazuhiko; Okumura, Ryo; Hata, Masato; Takeshita, Hiroshi; Nakajima, Ryohei (2010). "In Vitro Antifungal Activities of D11-2040, a β-1,6-Glucan Inhibitor, with or without Currently Available Antifungal Drugs". Biological & Pharmaceutical Bulletin 33 (2): 192–7. doi:10.1248/bpb.33.192. PMID 20118539.
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