Chemistry:Diosmetin

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Diosmetin
Diosmetin structure
Ball-and-stick model of diosmetin
Names
IUPAC name
3′,5,7-Trihydroxy-4′-methoxyflavone
Systematic IUPAC name
5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-benzopyran-4-one
Other names
Luteolin 4′-methyl ether
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
UNII
Properties
C16H12O6
Molar mass 300.26 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references
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Diosmetin, also known as 5,7,3′-trihydroxy-4′-methoxyflavone, is an O-methylated flavone, a chemical compound that can be found in the Caucasian vetch.[1]

It has been found to act as a weak TrkB receptor agonist.[2]

Glycosides

Diosmetin is the aglycone of diosmin.

See also

References

  1. Andreeva, O. A.; Ivashev, M. N.; Ozimina, I. I.; Maslikova, G. V. (1998). "Diosmetin glycosides from caucasian vetch: Isolation and study of biological activity". Pharmaceutical Chemistry Journal 32 (11): 595–597. doi:10.1007/BF02465832. https://doi.org/10.1007%2FBF02465832. 
  2. "A selective TrkB agonist with potent neurotrophic activities by 7,8-dihydroxyflavone". Proc. Natl. Acad. Sci. U.S.A. 107 (6): 2687–92. 2010. doi:10.1073/pnas.0913572107. PMID 20133810. Bibcode2010PNAS..107.2687J.