Chemistry:Dobesilic acid

From HandWiki
Dobesilic acid
File:Dobesilic acid.svg
Names
IUPAC name
2,5-Dihydroxybenzenesulfonic acid
Other names
Hydroquinonesulfonic acid
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
DrugBank
EC Number
  • 201-833-4
UNII
Properties
C6H6O5S
Molar mass 190.17 g·mol−1
Related compounds
Other cations
Calcium dobesilate
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references
Tracking categories (test):

Dobesilic acid is a chemical compound with the molecular formula C
6
H
6
O
5
S
. It is classified as both a phenol and a sulfonic acid.

Uses

Salts of dobesilic are used as pharmaceutical drugs. The calcium salt, calcium dobesilate, is used as a vasoprotective drug.[1][2] The diethylamine salt, etamsylate, is an antihemorrhagic agent.[3]

References

  1. "Calcium dobesilate for diabetic retinopathy: a systematic review and meta-analysis". Science China Life Sciences 58 (1): 101–7. January 2015. doi:10.1007/s11427-014-4792-1. PMID 25528255. 
  2. "Molecular Mechanisms and Treatment Strategies in Diabetic Nephropathy: New Avenues for Calcium Dobesilate-Free Radical Scavenger and Growth Factor Inhibition". BioMed Research International 2017. 2017. doi:10.1155/2017/1909258. PMID 29082239. 
  3. "Developmental outcome of the use of etamsylate for prevention of periventricular haemorrhage in a randomised controlled trial". Archives of Disease in Childhood. Fetal and Neonatal Edition 90 (1): F31–F35. January 2005. doi:10.1136/adc.2003.035790. PMID 15613570.