Chemistry:Flopristin
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Names | |
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IUPAC name
(7R,10R,11R,12Z,17Z,19Z,21S,23R)-23-fluoro-21-hydroxy-11,19-dimethyl-10-propan-2-yl-9,26-dioxa-3,15,28-triazatricyclo[23.2.1.03,7]octacosa-1(27),12,17,19,25(28)-pentaene-2,8,14-trione
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Other names
(16R)-16-Desoxy-16-fluoropristinamycin IIB; RPR 132552; RPR 132552A
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Identifiers | |
3D model (JSmol)
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ChemSpider | |
EC Number |
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PubChem CID
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UNII | |
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Properties | |
C28H38FN3O6 | |
Molar mass | 531.625 g·mol−1 |
Hazards | |
GHS pictograms | ![]() ![]() |
GHS Signal word | Warning |
H302, H312, H317, H332, H341 | |
P201, P202, P261, P264, P270, P271, P272, P280, P281, P301+312, P302+352, P304+312, P304+340, P308+313, P312, P321, P322, P330, P333+313, P363, P405, P501 | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
Infobox references | |
Tracking categories (test):
Flopristin is a semi-synthetic antibiotic of the streptogramin A class. It is a fluorinated derivative of pristinamycin IIB.[citation needed]
Flopristin is one of the components of the experimental drug NXL103.[1]
References
- ↑ Pankuch, Glenn A.; Kelly, Linda M.; Lin, Gengrong; Bryskier, Andre; Couturier, Catherine; Jacobs, Michael R.; Appelbaum, Peter C. (2003). "Activities of a new oral streptogramin, XRP 2868, compared to those of other agents against Streptococcus pneumoniae and Haemophilus species". Antimicrobial Agents and Chemotherapy 47 (10): 3270–3274. doi:10.1128/AAC.47.10.3270-3274.2003. PMID 14506040.
![]() | Original source: https://en.wikipedia.org/wiki/Flopristin.
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