Chemistry:Furanomycin
From HandWiki
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| Systematic IUPAC name
(S)-Amino[(2R,5S)-5-methyl-2,5-dihydrofuran-2-yl]acetic acid | |
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| Properties | |
| C7H11NO3 | |
| Molar mass | 157.169 g·mol−1 |
| Density | 1.238 g/mL |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
 verify (what is   ?)
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 | This article is missing information about natural sources (Streptomyces L-803 & Pseudomonas fluorescens SBW25), purpose. (November 2023) |
Furanomycin[1] is an isoleucine—tRNA ligase inhibitor.[2]
References
- ↑ Katagiri, Ken; Tori, Kazuo; Kimura, Yasuo; Yoshida, Tadashi; Nagasaki, Tohru; Minato, Hitoshi (1967). "A New Antibiotic. Furanomycin, an Isoleucine Antagonist". Journal of Medicinal Chemistry 10 (6): 1149–1154. doi:10.1021/jm00318a035. PMID 4861779.
- ↑ "Effect of furanomycin on the synthesis of isoleucyl-tRNA". Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis 195 (1): 244–245. November 1969. doi:10.1016/0005-2787(69)90621-2. PMID 4982424.
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