Chemistry:Gilvocarcin V
From HandWiki
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| IUPAC name
4-[3,4-dihydroxy-5-(1-hydroxyethyl)oxolan-2-yl]-8-ethenyl-1-hydroxy-10,12-dimethoxynaphtho[1,2-c]isochromen-6-one[1]
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| Other names | |
| Identifiers | |
3D model (JSmol)
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| ChemSpider | |
PubChem CID
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| Properties | |
| C27H26O9 | |
| Molar mass | 494.496 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| Infobox references | |
Gilvocarcin V is an antitumor agent and an antibiotic which is active against Gram-positive bacteria with the molecular formula C27H26O9.[3][4]Gilvocarcin V is produced by the bacterium Streptomyces griseoflavus and other Streptomyces bacteria.[3][4][1][5][6] Gilvocarcin V is a strong inhibitor of the DNA synthesis.[6]
References
- ↑ 1.0 1.1 1.2 "Gilvocarcin V" (in en). Pubchem.ncbi.NLM.nih.gov. https://pubchem.ncbi.nlm.nih.gov/compound/Gilvocarcin-V#section=3D-Conformer.
- ↑ 2.0 2.1 2.2 Gilvocarcin V (Anandimycin A, Toromycin B, Antibiotic 1072B), CAS [77879-90-4 | BIOZOL]. https://www.biozol.de/de/product/USB-G2034-45D.
- ↑ 3.0 3.1 (in en) Comprehensive Natural Products II: Chemistry and Biology. Elsevier. 5 March 2010. p. 257. ISBN 978-0-08-045382-8.
- ↑ 4.0 4.1 Buckingham, John (1987) (in en). Dictionary of Organic Compounds. Taylor & Francis. p. 359. ISBN 978-0-412-17050-8.
- ↑ Fischer, Carsten; Lipata, Fredilyn; Rohr, Jürgen (1 July 2003). "The Complete Gene Cluster of the Antitumor Agent Gilvocarcin V and Its Implication for the Biosynthesis of the Gilvocarcins". Journal of the American Chemical Society 125 (26): 7818–7819. doi:10.1021/ja034781q. PMID 12822997.
- ↑ 6.0 6.1 (in en) Progress in Medicinal Chemistry. Elsevier. 1 January 1985. p. 20. ISBN 978-0-08-086270-5.
Further reading
- Gillum, Karen D. (1988) (in en). Lethal and Mutagenic Effects of Antitumor Agent Gilvocarcin V Photosensitization on Escherichia Coli K-12/343/120. Texas Southern University. https://books.google.com/books?id=qpZdNwAACAAJ.
- Publishers, Bentham Science (November 1997) (in en). Current Organic Chemistry. Bentham Science Publishers. p. 408.
- (in en) Transferases—Advances in Research and Application: 2012 Edition. ScholarlyEditions. 26 December 2012. p. 137. ISBN 978-1-4649-9789-1.
- Diana, Patrizia; Cirrincione, Girolamo (9 February 2015) (in en). Biosynthesis of Heterocycles: From Isolation to Gene Cluster. John Wiley & Sons. p. 585. ISBN 978-1-118-02867-4.
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