Chemistry:Glabridin
From HandWiki
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| IUPAC name
(3R)-6′′,6′′-Dimethyl-6′′H-pyrano[2′′,3′′:7,8]isoflavan-2′,4′-diol
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| Systematic IUPAC name
4-[(3R)-8,8-Dimethyl-3,4-dihydro-2H,8H-(benzo[1,2-b:3,4-b′]dipyran)-3-yl]benzene-1,3-diol | |
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3D model (JSmol)
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PubChem CID
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| Properties | |
| C20H20O4 | |
| Molar mass | 324.376 g·mol−1 |
| Appearance | Yellowish-brown powder |
| Melting point | 238–240 °C (460–464 °F; 511–513 K)[1] |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
 verify (what is   ?)
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| Infobox references | |
Glabridin is a chemical compound that is found in the root extract of licorice (Glycyrrhiza glabra).[2] Glabridin is an isoflavane, a type of isoflavonoid. This product is part of a larger family of plant-derived molecules, the natural phenols. Glabridin effectively inhibits platelet activation, so it might become therapeutic agent for thromboembolic disorders.[3]
It is used as an ingredient in cosmetics and is listed in International Nomenclature of Cosmetic Ingredients (INCI).
Glabridin is yellowish-brown powder. It is insoluble in water, but soluble in organic solvents such as propylene glycol.
See also
References
- ↑ SciFinder Record for CAS#59870-68-7
- ↑ "Isoflavan derivatives from Glycyrrhiza glabra (licorice)". Heterocycles 43 (3): 581–588. 1996.
- ↑ "Glabridin, a Bioactive Flavonoid from Licorice, Effectively Inhibits Platelet Activation in Humans and Mice". International Journal of Molecular Sciences 23 (19): 11372. September 2022. doi:10.3390/ijms231911372. PMID 36232674.
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