Chemistry:Gougerotin
From HandWiki
Short description: Chemical compound
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| Formula | C16H25N7O8 |
| Molar mass | 443.417 g·mol−1 |
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Gougerotin is a water-soluble pyrimidine-based antibiotic which is produced by the bacteria Streptomyces graminearus and Streptomyces gougerotii.[1][2][3][4] Gougerotin is named after the dermatologist Henri-Eugène Gougerot.[2] Gougerotin has activity against Gram-positive and Gram-negative bacteria as well as against viruses.[2]
References
- ↑ "Gougerotin". Mechanism of Action of Antimicrobial and Antitumor Agents. 1975. pp. 448–458. doi:10.1007/978-3-642-46304-4_29. ISBN 978-3-642-46306-8.
- ↑ 2.0 2.1 2.2 (in de) Gougerotin. https://www.spektrum.de/lexikon/biologie/gougerotin/29072.
- ↑ (in en) Comprehensive Natural Products III. Elsevier. 22 July 2020. p. 528. ISBN 978-0-08-102691-5.
- ↑ (in de) Gougerotin. https://www.spektrum.de/lexikon/biochemie/gougerotin/2654.
Further reading
- "Gougerotin, a specific inhibitor of protein synthesis". Biochimica et Biophysica Acta (BBA) - Specialized Section on Nucleic Acids and Related Subjects 76: 636–8. December 1963. doi:10.1016/0926-6550(63)90092-6. PMID 14099625.
- "Gougerotin—an inhibitor of protein synthesis and auxin-induced elongation in plants". Phytochemistry 9 (3): 545–547. March 1970. doi:10.1016/S0031-9422(00)85687-3. Bibcode: 1970PChem...9..545B.
- (in en) Mechanism of Action. Springer Science & Business Media. 6 December 2012. p. 281. ISBN 978-3-642-46051-7.
- "(G-3H)gougerotin binding to ribosomes. Heterogeneity of eukaryotic ribosomes". European Journal of Biochemistry 44 (2): 445–53. May 1974. doi:10.1111/j.1432-1033.1974.tb03502.x. PMID 4600364.
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