Chemistry:Harmalol
From HandWiki
Harmalol is a bioactive β-carboline and a member of the harmala alkaloids.[1][2]
Pharmacology
Pharmacokinetics
The elimination half-life of harmalol has been reported to be 30 to 49 hours.[3]
Society and culture
Legal status
Australia
Harmala alkaloids are considered Schedule 9 prohibited substances under the Poisons Standard (October 2015).[4] A Schedule 9 substance is a substance which may be abused or misused, the manufacture, possession, sale or use of which should be prohibited by law except when required for medical or scientific research, or for analytical, teaching or training purposes with approval of Commonwealth and/or State or Territory Health Authorities.[4]
Canada
Harmalol is a controlled substance in Canada.[5]
See also
References
- ↑ "Binding of alkaloid harmalol to DNA: photophysical and calorimetric approach.". J Photochem Photobiol B 130: 272–80. 2014. doi:10.1016/j.jphotobiol.2013.11.021. PMID 24368411. Bibcode: 2014JPPB..130..272S.
- ↑ "Harmaline and harmalol inhibit the carcinogen-activating enzyme CYP1A1 via transcriptional and posttranslational mechanisms.". Food Chem Toxicol 50 (2): 353–62. 2012. doi:10.1016/j.fct.2011.10.052. PMID 22037238.
- ↑ "Toxicokinetics and Toxicodynamics of Ayahuasca Alkaloids N,N-Dimethyltryptamine (DMT), Harmine, Harmaline and Tetrahydroharmine: Clinical and Forensic Impact". Pharmaceuticals (Basel) 13 (11): 334. October 2020. doi:10.3390/ph13110334. PMID 33114119.
- ↑ 4.0 4.1 Poisons Standard October 2015 https://www.comlaw.gov.au/Details/F2015L01534
- ↑ "Controlled Drugs and Substances Act". https://laws-lois.justice.gc.ca/eng/acts/c-38.8/FullText.html.
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