Chemistry:Histamine glutarimide

From HandWiki
Short description: Chemical compound

Histamine glutarimide
Clinical data
Other namesXC-8
Legal status
Legal status
  • Investigational
Identifiers
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
Chemical and physical data
FormulaC10H13N3O2
Molar mass207.233 g·mol−1
3D model (JSmol)

Histamine glutarimide is an investigational new drug that is being evaluated for the treatment of cough in acute respiratory infection.[1][2] It is a glutaminyl cyclase inhibitor.[3]

References

  1. "Histamine glutarimide - EURRUS Biotech". AdisInsight. Springer Nature Switzerland AG. https://adisinsight.springer.com/drugs/800047677. 
  2. Clinical trial number NCT05273619 for "Efficacy and Safety of XC8, Film-coated Tablets, 40 mg in Patients With Dry Non-productive Cough Against Acute Respiratory Viral Infection" at ClinicalTrials.gov
  3. "New Anti-Chemokine Oral Drug XC8 in the Treatment of Asthma Patients with Poor Response to Corticosteroids: Results of a Phase 2A Randomized Controlled Clinical Trial". Pulmonary Therapy 6 (2): 351–369. December 2020. doi:10.1007/s41030-020-00134-5. PMID 33095411.