Chemistry:Hydroxymethyl group

From HandWiki
Hydroxymethyl group

Hydroxymethyl group covalently bonded to an R group
Names
IUPAC name
Hydroxymethyl group
Other names
Methanol radical
Identifiers
3D model (JSmol)
ChemSpider
Properties
–CH
2
OH
Molar mass 31.034 g·mol−1
Thermochemistry
−9 kJ/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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The hydroxymethyl group is a substituent with the structural formula –CH
2
–OH
. It consists of a methylene bridge (–CH
2
unit) bonded to a hydroxyl group (–OH). This makes the hydroxymethyl group an alcohol. It has the identical chemical formula with the methoxy group (–O–CH
3
) that differs only in the attachment site and orientation to the rest of the molecule. However, their chemical properties are different.[1][2]

Hydroxymethyl is the side chain of encoded amino acid serine.[3]

References

  1. NAMING ORGANIC COMPOUNDS. p. 37. https://www.kpu.ca/sites/default/files/downloads/sup08.pdf. Retrieved 2022-08-08. 
  2. Dong, Hao; Zheng, Erjin; Niu, Zhiyin; Zhang, Xiaoyu; Lin, Yi-Yu; Jain, Priyesh; Yu, Qiuming (2020-04-15). "Hydroxymethyl-Functionalized PEDOT-MeOH:PSS for Perovskite Solar Cells". ACS Applied Materials & Interfaces 12 (15): 17571–17582. doi:10.1021/acsami.0c01756. ISSN 1944-8252. PMID 32204591. 
  3. Perczel, András; Farkas, Ödön; Csizmadia, Imre G. (1996-01-01). "Peptide Models. 18. Hydroxymethyl Side-Chain Induced Backbone Conformational Shifts of l -Serine Amide. All ab Initio Conformers of For- l -Ser-NH 2" (in en). Journal of the American Chemical Society 118 (33): 7809–7817. doi:10.1021/ja960464q. ISSN 0002-7863. https://pubs.acs.org/doi/10.1021/ja960464q. Retrieved 2022-08-08.