Chemistry:IR3535
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| Names | |
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| IUPAC name
Ethyl N-acetyl-N-butyl-β-alaninate
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Other names
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| Identifiers | |
3D model (JSmol)
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| ChemSpider | |
PubChem CID
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| Properties | |
| C11H21NO3 | |
| Molar mass | 215.293 g·mol−1 |
| Appearance | Colourless liquid |
| Odor | Almost odorless |
| Density | 0.998 g/cm3 (at 20 °C) |
| 70 g/L (at 20 °C) | |
| Solubility in Acetone, ethyl acetate, dichloromethane, n-heptane, methanol, p-xylene | >250 g/L (at RT) |
| log P | 1.7 (at 23 °C) |
| Hazards | |
| GHS pictograms | 
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| GHS Signal word | Warning |
| H319 | |
| P280, P305+351+338, P337+313 | |
| Flash point | 159 °C (318 °F; 432 K) |
| Lethal dose or concentration (LD, LC): | |
LD50 (median dose)
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Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
 verify (what is   ?)
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| Infobox references | |
IR3535 (Insect Repellent 3535), also known by the non-proprietary name ethyl butylacetylaminopropionate, is one of the most common active ingredients in insect repellents. As it is solely a repellent it has no killing action and does not give rise to selection pressure or development of resistance.[1] It is a colourless and almost odourless oil and is intended to be applied to the skin (humans and animals).[1] [2] It has a broad efficacy against various insects like mosquitoes, ticks, lice, and other bugs.[1] [2] [3]In comparison to other insect repellent active ingredients, IR3535 is safe for use even on infants, pregnant and breastfeeding women. It is biodegradable and completely degraded in the environment within a very short time.[1]
IR3535 is a registered trademark of Merck KGaA.[4][5]
Chemistry
The structure of IR3535 is based on beta-alanine.[6] The EPA has classified IR3535 as a biochemical substance (biopesticide)[7] based on the fact that it is "functionally identical" to beta alanine. [8]
References
- ↑ 1.0 1.1 1.2 1.3 EU Assessment Report IR3535
- ↑ 2.0 2.1 EPA Technical Document IR3535
- ↑ EPA Fact Sheet IR3535
- ↑ "Insect Repellent IR3535". https://www.merckgroup.com/en/s/insect-repellent.html.
- ↑ "EPA, Draft Pesticide Product label for IR3535". https://www3.epa.gov/pesticides/chem_search/ppls/070759-00002-20071030.pdf.
- ↑ EPA: Similarity to beta-alanine
- ↑ EPA: Regulating Biopesticides
- ↑ EPA: IR3535 technical document
External links
- EPA: Active Ingredients Found in Insect Repellents
- CDC: Updated Information regarding Insect Repellents
- J. Med. Entomol. 39(6): 895-899 (2002)
- Tick Bite Prevention & the Use of Insect Repellents
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