Chemistry:Isovoacristine

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Isovoacristine is an ibogan-type indole alkaloid, primarily isolated from plants of the Tabernaemontana genus such as Tabernaemontana calcarea,[1] Tabernaemontana divaricata,[2] and Tabernaemontana laurifolia.[3] Is has anticholinergic and antihistaminic properties.[4] It also has demonstrated cytotoxic effects against the A2780 ovarian cancer cell line.[5]

See also

References

  1. ↑ "New cytotoxic indole alkaloids from Tabernaemontana calcarea from the Madagascar rainforest". Journal of Natural Products 66 (4): 528–31. April 2003. doi:10.1021/np020548e. PMID 12713407. Bibcode: 2003JNAtP..66..528P. 
  2. ↑ "Indole alkaloids from Tabernaemontana divaricata". Phytochemistry 30 (5): 1740–1741. January 1991. doi:10.1016/0031-9422(91)84254-P. Bibcode: 1991PChem..30.1740A. 
  3. ↑ "Isovoacristine: a new iboga-type alkaloid from Tabernaemontana laurifolia.". Chemistry & Industry (London, United Kingdom) 51: 2064. 1965. 
  4. ↑ Herbalism, Phytochemistry and Ethnopharmacology. 2011. pp. 45. doi:10.1201/b10878. ISBN 978-1-4398-5361-0. 
  5. ↑ "Molecular Human Targets of Bioactive Alkaloid-Type Compounds from Tabernaemontana cymose Jacq". Molecules (Basel, Switzerland) 26 (12): 3765. June 2021. doi:10.3390/molecules26123765. PMID 34205626. 



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