Chemistry:Kairine
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| Preferred IUPAC name
1-Methyl-1,2,3,4-tetrahydroquinolin-8-ol | |
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| Properties | |
| C10H13NO | |
| Molar mass | 163.220 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
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Kairine is a derivative of tetrahydroquinoline which was first described by Wilhelm Fischer in 1883. Its name comes from the Greek kairos, meaning "the right time".[1] It is an antipyretic, formerly used against typhoid fever, but now largely obsolete due to severe side effects. Both kairine and its N-ethyl homolog show similar antipyretic activity.[2][3][4][5]
See also
References
- ↑ W.E.Flood (1963). The Origins of Chemical Names. Oldbourne Book Co Ltd. pp. 126.
- ↑ Fischer, Wilhelm (1883). "On Kairine and Kairoline". New Remedies 12 (2): 41. https://books.google.com/books?id=UVBHAQAAMAAJ&pg=PA41.
- ↑ Fruitnight, J. Henry (1886). "Kairine and Antipyrine". Medical Record 29 (23): 646–648. https://books.google.com/books?id=xNM-AQAAMAAJ&pg=PA646.
- ↑ Bockmuhl M, Dorzbach E. Antipyretics of the tetrahydroquinoline series. Med. u. Chem. (1942) 4: 179-212.
- ↑ Slater, Leo Barney (2009). War and Disease: Biomedical Research on Malaria in the Twentieth Century. Rutgers University Press. p. 26. ISBN 978-0-8135-4438-0.
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