Chemistry:Lactivicin
From HandWiki
Short description: Chemical compound
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| IUPAC name
2-(4-Acetamido-3-oxo-1,2-oxazolidin-2-yl)-5-oxooxolane-2-carboxylic acid
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3D model (JSmol)
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PubChem CID
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| Properties | |
| C10H12N2O7 | |
| Molar mass | 272.213 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| Infobox references | |
Lactivicin is a non-beta-lactam antibiotic that is active against a range of Gram-positive and Gram-negative bacteria.[1] Lactivicin demonstrates a similar affinity for penicillin-binding proteins to beta-lactam antibiotics and is also susceptible to beta-lactamase enzymes.[2]
References
- ↑ "Lactivicin, a naturally occurring non-beta-lactam antibiotic having beta-lactam-like action: biological activities and mode of action". J. Antibiot. 42 (10): 84–93. 1989. doi:10.7164/antibiotics.42.84. PMID 2493440.
- ↑ "Structure of lactivicin, an antibiotic having a new nucleus and similar biological activities to β-lactam antibiotics". Tetrahedron Letters 27 (51): 6229–6232. 1986. doi:10.1016/S0040-4039(00)85439-8.
External links
- "Mechanism Of Unusual Antibiotic". Chemical & Engineering News 85 (33): 13. August 13, 2007. http://pubs.acs.org/cen/news/85/i33/8533news7.html.
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