Chemistry:Lascufloxacin
From HandWiki
Short description: Chemical compound
| Clinical data | |
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| Trade names | Lasvic |
| Other names | KRP-AM1977 |
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| Formula | C21H24F3N3O4 |
| Molar mass | 439.435 g·mol−1 |
| 3D model (JSmol) | |
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Lascufloxacin (trade name Lasvic) is an fluoroquinolone antibiotic drug for the treatment of bacterial infections. It has been approved since 2019 in Japan[1] to treat community-acquired pneumonia, otorhinolaryngological infections, and respiratory tract infections.[2]
It has activity against various Gram-positive bacteria including Streptococcus pneumoniae[3] and Streptococcus anginosus.[4]
References
- ↑ "Kyorin Pharmaceutical Receives Marketing Approval for Oral Quinolone Antibacterial Agent Lasvic Tablets 75 mg" (PDF) (Press release). Kyorin Pharmaceutical Co. September 20, 2019. Retrieved July 3, 2021.
- ↑ "Lascufloxacin - Kyorin Pharmaceutical". Adis Insight. https://adisinsight.springer.com/drugs/800035339.
- ↑ "In Vitro Activity of Lascufloxacin against Streptococcus pneumoniae with Mutations in the Quinolone Resistance-Determining Regions". Antimicrob Agents Chemother 62 (4). April 2018. doi:10.1128/AAC.01971-17. PMID 29439959.
- ↑ "In vitro activity of lascufloxacin, a novel fluoroquinolone antibacterial agent, against various clinical isolates of anaerobes and Streptococcus anginosus group". Anaerobe 54: 61–64. December 2018. doi:10.1016/j.anaerobe.2018.08.002. PMID 30114441.

