Chemistry:Leptosin
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| IUPAC name
(2Z)-2-[(3,4-dihydroxyphenyl)methylidene]-7-methoxy-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1-benzofuran-3-one
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3D model (JSmol)
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| Properties | |
| C22H22O11 | |
| Molar mass | 462.407 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| Infobox references | |
Leptosin is an aurone glycoside first reported from the leaves of Flemingia strobilifera, commonly known as kusrunt.[1] Leptosin has also been found in Coreopsis species, including Coreopsis lanceolata[2] and Coreopsis grandiflora.[3] Another accepted name for this chemical is leptosidin 7-O-β-D-glucopyranoside.[2] Leptosperin was originally called Leptosin before being renamed to the name it has now.
Research
In a 2021 study, Leptosin was isolated from Coreopsis lanceolata flowers and was found to have antioxidant activity. Leptosin was then tested in zebrafish and the results suggested that the chemical may have potential in diabetes-related research.[2]
References
- ↑ Nigam, S.; Saxena, V. (February 1975). "ISOLATION AND STUDY OF THE AURONE GLYCOSIDE LEPTOSIN FROM THE LEAVES OF FLEMENGIA STROBILIFERA" (in en). Planta Medica 27 (1): 98–100. doi:10.1055/s-0028-1097768. ISSN 0032-0943. PMID 1161882. Bibcode: 1975PlMed..27...98N. http://www.thieme-connect.de/DOI/DOI?10.1055/s-0028-1097768.
- ↑ 2.0 2.1 2.2 Kim, Hyoung-Geun; Nam, Youn Hee; Jung, Young Sung; Oh, Seon Min; Nguyen, Trong Nguyen; Lee, Min-Ho; Kim, Dae-Ok; Kang, Tong Ho et al. (2021-10-09). "Aurones and Flavonols from Coreopsis lanceolata L. Flowers and Their Anti-Oxidant, Pro-Inflammatory Inhibition Effects, and Recovery Effects on Alloxan-Induced Pancreatic Islets in Zebrafish" (in en). Molecules 26 (20): 6098. doi:10.3390/molecules26206098. ISSN 1420-3049. PMID 34684679.
- ↑ Crawford, Daniel J.; Smith, Edwin B. (April 1980). "Flavonoid Chemistry of Coreopsis Grandiflora (Compositae)". Brittonia 32 (2): 154. doi:10.2307/2806783. Bibcode: 1980Britt..32..154C. http://link.springer.com/10.2307/2806783.
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