Chemistry:Livagen

From HandWiki

Livagen is a tetrapeptide with the sequence KEDA or Lys-Glu-Asp-Ala. It is one of a number of small peptides developed in Russia in the late 1990s and early 2000s which have antiinflammatory and purported anti-aging effects, and are now widely sold over the internet as anti-aging products though with relatively limited evidence to support these claims.[1][2][3][4][5][6][7][8]

See also

  • Cortagen
  • Epitalon
  • GHK-Cu
  • KPV tripeptide
  • Pinealon
  • Vesugen
  • Vladimir Khavinson

References

  1. "[Tissue-specific action of peptides in tissue culture of rats of various ages]". Advances in Gerontology = Uspekhi Gerontologii 9: 95–100. 2002. PMID 12096446. 
  2. "Effects of short peptides on lymphocyte chromatin in senile subjects". Bulletin of Experimental Biology and Medicine 137 (1): 78–81. January 2004. doi:10.1023/b:bebm.0000024393.40560.05. PMID 15085253. 
  3. "Anti-aging peptide bioregulators induce reactivation of chromatin". Georgian Medical News (133): 111–115. April 2006. PMID 16705247. 
  4. "Activation of pericentromeric and telomeric heterochromatin in cultured lymphocytes from old individuals". Annals of the New York Academy of Sciences 1100 (1): 387–399. April 2007. doi:10.1196/annals.1395.043. PMID 17460203. Bibcode2007NYASA1100..387L. 
  5. "[The effect of heavy metal ions and peptide bioregulators on the expression of chromosome fragile sites in the individuals of different age groups and breast cancer patients]". Georgian Medical News (162): 11–14. September 2008. PMID 18830022. 
  6. "[Genomic instability in atherosclerosis]". Georgian Medical News (236): 82–86. November 2014. PMID 25541832. 
  7. "[The influence of polypeptide liver complex and tetrapeptide KEDA on organism physiological function in norm and age-related pathology.]". Advances in Gerontology = Uspekhi Gerontologii 33 (1): 159–164. 2020. PMID 32362099. 
  8. "Epigenetic Modification Under the Influence of Peptide Bioregulators on the "Old" Chromatin". Georgian Medical News (335): 79–83. February 2023. PMID 37042594.