Chemistry:Lucimycin
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C36H53NO13 | |
Molar mass | 707.80492 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
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Lucimycin (INN, also known as lucensomycin and etruscomycin) is a macrolide antibiotic synthesized by the bacterium Streptomyces lucensis. It belongs to the group of polyene antimycotics and was first isolated in the 1960s. It has seen only limited clinical use.
Lucimycin is also produced by the Streptomyces cyanogenus S136, where the full biosynthetic gene cluster for the production of this compound was described.[1]
References
- ↑ "Eliciting the silent lucensomycin biosynthetic pathway in Streptomyces cyanogenus S136 via manipulation of the global regulatory gene adpA". Scientific Reports 11 (1): 3507. February 2021. doi:10.1038/s41598-021-82934-6. PMID 33568768. Bibcode: 2021NatSR..11.3507Y.
Further reading
- Dictionary of Pharmacological Agents. 1997. p. 1239. ISBN 9780412466304. https://books.google.com/books?id=A0THacd46ZsC&dq=lucensomycin&pg=PA1239.
Original source: https://en.wikipedia.org/wiki/Lucimycin.
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