Chemistry:Mazisotine
From HandWiki
Mazisotine (LY3556050, CNTX-0290) is a chemical compound which acts as an agonist at somatostatin receptor 4. It has analgesic effects and has been researched for the treatment of pain associated with arthritis and neuropathic pain. It was not pursued for human medical use following disappointing results in Phase II clinical trials, but continues to be used in research into the role of SST4 receptors in pain perception.[1][2]
See also
- J-2156
- NNC 26-9100
References
- ↑ "Preclinical Evaluation of Human Somatostatin Receptor 4 (hSSTR4) Agonist CNTX-0290 for Mixed Pain Conditions.". The Journal of Pain 20 (4): S73. April 2019. doi:10.1016/j.jpain.2019.02.092.
- ↑ "Diastereoselective Cyclopropanation with Secondary Diazoacetamides to Access endo-Azabicyclo[3.1.0hexane-6-carboxamides"]. Organic Letters 28 (9): 3063–3067. March 2026. doi:10.1021/acs.orglett.6c00392. PMID 41729728.
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