Chemistry:Megazol
From HandWiki
Short description: Chemical compound
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| Formula | C6H6N6O2S |
| Molar mass | 226.21 g·mol−1 |
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Megazol (CL 64855) is a nitroimidazole based drug that cures some protozoan infections.
A study of nitroimidazoles found the drug extremely effective against T. cruzi and T. brucei which cause Chagas disease and African sleeping sickness, respectively. The drug is considerably more effective than standard benznidazole therapy (for Chagas) which is considered the gold standard.[1] This is despite that other nitroimidazoles proved ineffective against these pathogens.[citation needed]
References
- ↑ "Activation of benznidazole by trypanosomal type I nitroreductases results in glyoxal formation". Antimicrobial Agents and Chemotherapy 56 (1): 115–23. January 2012. doi:10.1128/AAC.05135-11. PMID 22037852.
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