Chemistry:Merafloxacin
From HandWiki
Short description: Chemical compound
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Formula | C19H23F2N3O3 |
Molar mass | 379.408 g·mol−1 |
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Merafloxacin is a fluoroquinolone antibacterial that inhibits the pseudoknot formation which is necessary for the frameshift in the SARS-CoV-2 genome.[1] It is a promising drug candidate for SARS-CoV-2.[2]
References
- ↑ "Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome". Science 372 (6548): 1306–1313. June 2021. doi:10.1126/science.abf3546. PMID 34029205. Bibcode: 2021Sci...372.1306B.
- ↑ "Restriction of SARS-CoV-2 Replication by Targeting Programmed -1 Ribosomal Frameshifting In Vitro". bioRxiv. October 2020. doi:10.1101/2020.10.21.349225. PMID 33106809.
Original source: https://en.wikipedia.org/wiki/Merafloxacin.
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