Chemistry:Molvizarin
From HandWiki
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| IUPAC name
(2S)-4-[(2R,11R)-2,11-Dihydroxy-11-[(2R,5R)-5-[(2R,5R)-5-[(1S)-1-hydroxyundecyl]oxolan-2-yl]oxolan-2-yl]undecyl]-2-methyl-2H-furan-5-one[1]
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3D model (JSmol)
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PubChem CID
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| Properties | |
| C35H62O7 | |
| Molar mass | 594.874 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| Infobox references | |
Tracking categories (test):
Molvizarin is a cytotoxic acetogenin derivate with the molecular formula C35H62O7 which has been isolated from the bark of the plant Annona cherimolia.[2][1][3][4][5] Molvizarin has in vitro activity against tumor cells.[6]
References
- ↑ 1.0 1.1 "Molvizarin" (in en). Pubchem.ncbi.NLM.nih.gov. https://pubchem.ncbi.nlm.nih.gov/compound/Molvizarin#section=3D-Status.
- ↑ Kintzios, Spiridon E.; Barberaki, Maria G. (15 January 2004) (in en). Plants that Fight Cancer. CRC Press. p. 79. ISBN 978-1-4200-2371-8.
- ↑ Cortes, Diego; Myint, Saw H.; Hocquemiller, Reynald (September 1991). "Molvizarin and motrilin: Two novel cytotoxic bis-tetrahydro-furanic γ-lactone acetogenins from Annona cherimolia". Tetrahedron 47 (38): 8195–8202. doi:10.1016/s0040-4020(01)91014-2.
- ↑ Xu, Jun-Ping (25 November 2016) (in en). Cancer Inhibitors from Chinese Natural Medicines. CRC Press. ISBN 978-1-315-34923-7. https://books.google.com/books?id=elFIDgAAQBAJ&dq=Molvizarin&pg=PT274.
- ↑ (in en) Issues in Materials and Manufacturing Research: 2011 Edition. ScholarlyEditions. 9 January 2012. p. 5103. ISBN 978-1-4649-6331-5.
- ↑ Nakanishi, Yuka; Chang, Fang-Rong; Liaw, Chih-Chuang; Wu, Yang-Chang; Bastow, Kenneth F.; Lee, Kuo-Hsiung (1 July 2003). "Acetogenins as Selective Inhibitors of the Human Ovarian 1A9 Tumor Cell Line". Journal of Medicinal Chemistry 46 (15): 3185–3188. doi:10.1021/jm020548b. PMID 12852747.
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