Chemistry:Nebacumab

From HandWiki
Short description: Monoclonal antibody
Nebacumab
Monoclonal antibody
TypeWhole antibody
SourceHuman
Targetendotoxin
Clinical data
AHFS/Drugs.comInternational Drug Names
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ChemSpider
  • none
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KEGG
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Nebacumab is a human monoclonal antibody developed for the treatment of sepsis.[1] It has been withdrawn in 1993 because it failed to reduce mortality in clinical trials.[2]

References

  1. "Randomized, placebo-controlled trial of HA-1A, a human monoclonal antibody to endotoxin, in children with meningococcal septic shock. European Pediatric Meningococcal Septic Shock Trial Study Group". Clinical Infectious Diseases 28 (4): 770–7. April 1999. doi:10.1086/515184. PMID 10825037. 
  2. WHO: Consolidated List of Products