Chemistry:Urtoxazumab
From HandWiki
Short description: Monoclonal antibody
| Monoclonal antibody | |
|---|---|
| Type | Whole antibody |
| Source | Humanized (from mouse) |
| Target | E. coli Shiga-like toxin II B subunit |
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| CAS Number | |
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| Formula | C6414H9934N1718O2010S40 |
| Molar mass | 144556.44 g·mol−1 |
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Urtoxazumab is a humanized monoclonal antibody against diarrhoea caused by Escherichia coli, serotype O121. The drug is designed to bind to a toxin of this bacterium, so that it can be more easily broken down and eliminated from the body.[1][2]
References
- ↑ "International Nonproprietary Names for Pharmaceutical Substances (INN)". World Health Organization. http://whqlibdoc.who.int/druginfo/18_1_2004_INN.pdf.
- ↑ "Safety and pharmacokinetics of urtoxazumab, a humanized monoclonal antibody, against Shiga-like toxin 2 in healthy adults and in pediatric patients infected with Shiga-like toxin-producing Escherichia coli". Antimicrobial Agents and Chemotherapy 54 (1): 239–43. January 2010. doi:10.1128/AAC.00343-09. PMID 19822704.
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