Chemistry:Oxiperomide

From HandWiki
Short description: Chemical compound
Oxiperomide
Skeletal formula of oxiperomide
Clinical data
Routes of
administration
Oral
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
Chemical and physical data
FormulaC20H23N3O2
Molar mass337.423 g·mol−1
3D model (JSmol)

Oxiperomide is an antipsychotic.[1] Clinical trials demonstrated that it can reduce dyskinesia in patients with Parkinson's disease who are taking dopamine agonists without increasing Parkinsonian symptoms. It does this by selectively antagonizing dopamine receptors.[2][3] Further development of this drug is not available. It appears to have never been marketed.

See also

References

  1. "Oxiperomide". The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Dordrecht: Springer. 1990. ISBN 978-1-4757-2085-3. https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA916. 
  2. "Effect of new dopamine-blocking agent (oxiperomide) on drug-induced dyskinesias in Parkinson's disease and spontaneous dyskinesias". British Medical Journal 1 (6118): 954–956. April 1978. doi:10.1136/bmj.1.6118.954. PMID 638546. 
  3. "Oxiperomide in tardive dyskinesia". Journal of Neurology, Neurosurgery, and Psychiatry 43 (3): 264–267. March 1980. doi:10.1136/jnnp.43.3.264. PMID 7373324.