Chemistry:PD 144418
From HandWiki
Short description: Chemical compound
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| Formula | C18H22N2O |
| Molar mass | 282.387 g·mol−1 |
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PD 144418 or 1,2,3,6-tetrahydro-5-[3-(4-methylphenyl)-5-isoxazolyl]-1-propylpyridine is a potent and selective ligand for the sigma-1 receptor, with a reported binding affinity of Ki = 0.08 ± 0.01 nM, and 17 212 times selectivity over the sigma-2 receptor.[1]
References
- ↑ "The pharmacology of the novel and selective sigma ligand, PD 144418". Neuropharmacology 36 (1): 51–62. January 1997. doi:10.1016/S0028-3908(96)00161-X. PMID 9144641.
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